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Archiv fir Entwickelungs-Mechanik der Orgaiusmcn. etc.. Novem- ber 24, igo8. ^Scientia. xvi, p. 453. .s. Q and 10, — Show which they can be occupant becoming and rainy weather. iiR cotistruclion of slats and mechanism by opened, allowinff free access of air without lisible from witiiont, and closed for stormy (Knopf.) 766 WRIGHT: FATS AND LIPOIDS. IV. [New York Medical Journal. This and their sHght tinging with osmic acid, the very selective staining by the methods of Benda and others have led many histologists to suppose that they contain some lipoid, a fatty acid, in the form of a soap, I suppose. The pres- ence of crystals of fatty acids in benign tumors and various experiments have led White'' to conclude that it is the presence of cholesterin associated with them which limits their growth. This has its sug- gestiveness here, but it also has an affiliation with the part Can You Buy Viagra Online Legally Uk cholesterin plays in immunology, and it is liable to be an important consideration in the more scientific study of cancer. I cannot, of course, even allude to all the fields in which this subject has its place. All I wish to do is to supplement and direct to a more specific application the general considerations I have al- ready ventured on in a recent article^ on surface tensions. There I have alluded to the method by which Lord Rayleigh ascertained the radius of molecular action and its influence on the surface tension of fluids. He employed, it will be remembered, the surface of the fluid in a tub of water, over which he spread an extremely thin coating of oil. Camphor flakes thrown on water surfaces exhibit gyrations familiar to all ; thrown upon oil they are motionless. The degree of tenuity of the oily coating on the water was measured by the degree of motion im- parted to the flakes by the underlying water and from this the length of the radius of the dynamic influence of the molecules of water was deduced. Now let us imagine a fat like fluid coating an al- buminous body in the tissues. At once it is evident Can You Buy Viagra Online Legally Uk that the reaction of that body is dependent on the state of the fat like coating and the thickness of it. Beyond the radius of molecular action of the albu- minoid the lipoid is master of the situation. Within that radius the lipoid shares its government with the underlying albuminoid. In view of the extreme tenuity of a layer of oil (5 to 20 ,y .'■ for water) , which would allow any albuminous action to be manifested, it is questionable if tinctorial reactions are capable of revealing the combination in that condition which we must believe is the most essen- tial to the vital action of protoplasmic entities, be it cell or chromosome. That condition Can You Buy Viagra Online Legally Uk vi-hich ap- proaches nearest to a tenuity of coating represented by the radius of molecular action would be the most ■sensitive and the Can You Buy Viagra Online Legally Uk most efficient one. Thus far such light as we perceive is purely Can You Buy Viagra Online Legally Uk of a deductive nature. What direct evidence can be adduced that such in Can You Buy Viagra Online Legally Uk fact is the condition of combinations of albuminoid and lipoid? It must be confessed that its visible direct demonstration is impossible. That is, we cannot see entities Can You Buy Viagra Online Legally Uk so small with coatings so thin as those which are concerned, as we believe, in vital reactions. Yet there are adumbrations of this direct visible proof. Such are furnished by the revelations of the polariscope applied to the microscopic vision of certain lipoid combinations of cholesterin. lecithin, and neutral fat, as set forth in this country by the work of Adami" and published elsewhere by him' in * Journal of Pathology and Bacteriology , April, igio. *New York Medical Journal, October 15, 1910. ^Journal of the American Medical Association, February 9. 1907. ^Proceedings of the Royal Society of London, Biological Section. :9o6. p. 359. collaboration with Aschoff. This phenomenon of birefringency is known to rest upon the dynamic condition of certain layers which coat the surfaces of lipoalbuminous derivatives of tissue cells. Now this principle of double layers or triple layers or the many zoned composition of entities in the micro- chemistry of living tissue is no anomaly nor is it confined to fatlike material alone or to its combina- tions with the albuminoids. It is shadowed forth in the hull of the nut, in the shell, in the condensed outer layer of the kernel ; nay, it has been shown that the starch granules of the wheat kernel are each surrounded by an envelope which has to be disintegrated before any diastase can work on it. and so, one hull within the other, we reach the minute dimensions of the ultimate starch granules said to be about thirty or thirty-five micra in di- ameter. This phenomenon is attracting a great deal of at- tention in connection with fatty substances and it is well to point out the place it assumes in the general scheme of living things. The capsules of bacteria borrowed from their environment, nature's effort tc encapsulate foreign bodies, the sort of semihull that is formed around old tubercle, etc., should all be thought of as indicating that this putting another surface tension on lipoid drops is in line with put- ting another surface on more familiar entities like the walnut and the grain of wheat. The physical aspects of it should be viewed in all lights, and it is not out of place to cite here a reference to some work of Pickering.*