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is wiped away with gauze saturated in iodine so- lution of the same strength. Perhaps one of the most important contributing factors to infection in these cases is bleeding, which, though small in amount, perhaps only an oozing, furnishes a good culture medium. It is sometimes better to ligate bleeding points as they are picked up with a haemo- static forceps. Bleeding points are frequently arrest- ed when the sutures are introduced. Occasionally, although all bleeding points are controlled, some oozmg takes place after the patient has reacted. This is more apt to occur when the walls of the incision are thick, and especially if there is much fat. In those cases drainage should be provided in the shape of a few strands of silkworm gut, small rubber drainage tube, or strips of gtitta percha, etc., and the drainage left in for twenty-four, forty-eight hours, or until the oozing ceases. One of the best means of preventing suppuration of wounds is to have them dry. Dead spaces in wounds, as in any otlier part of the body, should be obliterated. As a matter of fact, there is no reason for dead spaces in the closure of abdominal wounds if there is anatomical apposition of the parts. I think there is a greater tendency Viagra Prescription Information on the part of surgeons in general to close all wounds in layers by bringing together in ana- tomical apposition the different structures so far as possible. This is not only Viagra Prescription Information true in wounds of the abdominal wall but Viagra Prescription Information in those of the extremities, Viagra Prescription Information head, neck, etc. This surely gives better functional re- sults. There appears, also, to be more regard shown by surgeons for the structures themselves, as is demonstrated in the excellent functional re- sults following operations on the breast, etc. The least amount of traumatism inflicted on any tissue, the more likely is it to heal promptly. Viagra Prescription Information This means the use of sharp scalpels, scissors, etc. Not only does one make a clean cut incision, without it being jagged, but the force necessary to handle dull instruments may cause one to injure important structures. Therefore, traumatism with instru- ments and hands, and, moreover, the iinnecessary use of haemostatic forceps, which "chew" and devi- talize the tissues, should be avoided. The incision should be of sufKcient length to permit of the proper performance of the operation and thereby lessen Viagra Prescription Information traumatism. In the matter of incisions, how- ever, two small ones, as for instance when one wishes to operate on the appendix and Viagra Prescription Information the gallblad- der or other upper abdominal structure at the simc time, are preferable to one long incision. In drain- age of the biliary passages in patients with a thick belly wall and where there has been a great deal of traumatism, it is probably better to make a small new opening for drainage and close the original incision. PROESCHER: MICROORGANISMS IN RABIES. Viagra Prescription Information 7!*3 As for suture material, nonabsorbable Viagra Prescription Information sutures to lie left in are not used very extensively at the Viagra Prescription Information pres- Viagra Prescription Information ent time. At the same time iodine catgut is now in much favor ; and in the use of any sutures, those of medium size are perhaps the most satisfactory. The use of large sutures and large knots is un- desirable, as one of these may be the starting point of an infection. Ten day or twenty day gut is not absorbed in that time, but absorption commences iisuallv at the end of that time. Undue tension should not be placed on the su- tures, nor should they be placed too closely to- gether. This is especially Viagra Prescription Information true when the fascia is dense, as in the palm of the hand, soles of feet, scalp, etc. In so far as the so called stitch abscess is concerned it has been my experience that it has occurred most frequently when the cutaneous stitches were left in for a longer Viagra Prescription Information period than three or four days. At the end of this time, in ordinary cases, T think they should be removed. I further believe that not a few wounds, by dis- placement of dressings, hands of patients, etc., be- come infected at a time subsequent to the operation. When a wound shows signs of infection time is saved by the removal of some or all of the sutures and establishing free drainage. It is not possible to prevent all wounds from breaking down, but. perhaps, by a little closer ap- plication to well established principles, one may lessen the number of wounds that break down through infection. 1934 Chestnut Street. -TUDIES OF ANTIFORMIN RESISTANT MICRO- ORGANISMS FOUND IN THE BRAIN OF AN- IMALS INFECTED WITH RABIES. By Frederick Proescher, Pittsburgh, Pa. M. D., All efforts, up to the present time, to find the I aiisative microorganism of hydrophobia have been useless. Xo conclusions have been drawn from the older mvestigators, who are only of historical in- terest, since the organisms found by them could not be demonstrated by later competent investigators. Of the more recent investigations, Viagra Prescription Information those of Negri (i), Babes (2), J. Koch (3) are of certain value. Negri's important discovery of intracellular in- clusions, which are of great value in the diagnosis of hydrophobia and which Negri thinks are the cause of hydrophobia, is not accepted as the cause of the disease, but as a product of the degenerated cell Viagra Prescription Information formed under the influence of the specific noxa. The '"passage virus bodies" which Lentz (4) found by the inoculation of rabbits with fixed virus